Endocrine Abstracts

The aim of the research was studying the influence of age and sex on the changes of bone mineral density detected on rats with experimental hyperthyroidism.Research object: Research is conducted on 180 white females and males rats of ‘Wistar’ breed. Animals were arranged in the 12 groups: six controls groups (CG) of pre-pubertal, reproductive and old males and females; six age-dependent groups of males and females rats getting L-...

The aim of this study is evaluating body composition in postmenopausal women depending on presence of vertebral fractures in their anamnesis.Materials and methods: We’ve examined 144 postmenopausal women aged 50–83 years (mean age – 62.9±0.7 years; mean height – 160.6±0.5 cm; mean weight – 71.9±1.2 kg). The patients were divided into two groups: group A – women without vertebral fractures (n=82), group ...

The aim: To study age-dependent changes of bone mineral density of females and males rats in remote terms after hyperthyroidism abolition.Research Object: Research is conducted on 180 white females and males rats of ‘Wistar’ breed. Animals were arranged in the 18 groups: six controls groups (CG) of pre-pubertal, reproductive and old males and females; six groups of rats with the experimental model hyperthyroidism (HTG); six groups of rats 30 da...

Disorders of bone tissue as a complication of hyperthyroidism now become accepted fact. On other side decreasing of serum levels of estrogens in postmenopausal women potentially may increase effects of thyroid hormones on bone tissue.The aim of our study was investigate with DXA the features of loss of bone mass in women suffering from thyrotoxicosis depending of age and thyrotoxicosis duration.Material and methods: There were exam...

Aim of research: To determine uric acid level in blood serum and incidents of hyperuricemia among women and men of different age and their relation with some components of metabolic syndrome.Object of research: Women (n=450) and men (n=120), age of examined patients was from 20 to 89 years old. They were divided into the following groups: I group (BMI=18.5–24.9), II group (BMI=25.0–29.9), III group (BMI=30.0–34.9), IV group (...

Aim of research: To determine uric acid level in blood serum and incidents of hyperuricemia in postmenopausal women and their relation with body mass index (BMI).Object of research: Patients of clinic by the physiology and pathology of bone and joint disease department and Ukrainian medical-scientific center of osteoporosis: postmenopausal women (n=134). They were divided in the following groups depending on BMI: I group (BMI=20.0–24.9) &#150...

Numerous hormonal and metabolic disorders caused by thyrotoxicosis lead to serious complications, so early diagnosis and adequate treatment becomes very important in warning of functional and organic changes in several organ systems, particularly in the structure of bone tissue.The aim was study of the effectiveness of calcium and alendronate for prevention and treatment of BMD losing in experimental models of thyreotoxicosis.Mater...

Objective: Postmenopausal period in women is associated with the accelerated bone loss, contributing to the development of osteoporosis, fractures and decreasing of quality and duration of life. The metabolic syndrome (MS), which includes obesity, dyslipidemia, hyperglycemia, and hypertension, is a major public health problem also.The purpose of our study was to reveal associations between tissue body composition, compounds of MS and BMD in postmenopausa...

Introduction: Vitamin D is important for bone and muscle development, function, and preservation. The serum 25OHD concentration is the best available clinical indicator of vitamin D status. The optimal serum 25OHD concentration is considered to be that level associated with maximal parathyroid hormone (PTH) suppression.The aim: To determine the frequency of vitamin D deficiency and insufficiency in patients of different region of Ukraine and to evaluate ...